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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKB2
All Species:
4.55
Human Site:
S726
Identified Species:
11.11
UniProt:
Q00653
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00653
NP_001070961.1
900
96749
S726
G
P
E
K
D
T
R
S
S
F
R
G
H
T
P
Chimpanzee
Pan troglodytes
XP_001168576
837
90846
L686
Q
L
A
E
D
V
K
L
Q
L
Y
K
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001104566
876
94023
S726
G
P
E
K
D
T
R
S
S
F
R
G
H
T
P
Dog
Lupus familis
XP_850995
899
96492
G726
G
P
E
R
D
A
R
G
S
S
R
G
H
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK5
899
96814
R726
G
P
E
R
D
T
Q
R
N
F
R
G
H
T
P
Rat
Rattus norvegicus
NP_001008350
898
96721
R725
G
P
E
T
D
T
Q
R
N
F
R
G
H
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98150
906
99648
P732
E
E
Q
E
E
A
G
P
R
Q
R
L
H
T
A
Frog
Xenopus laevis
O73630
958
105836
R777
R
P
H
C
A
M
K
R
R
Y
S
G
H
T
A
Zebra Danio
Brachydanio rerio
NP_001001840
902
98760
R743
G
V
F
N
P
R
K
R
P
A
A
G
H
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999819
1125
124026
E904
G
V
E
E
E
E
K
E
K
H
G
K
T
P
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.1
95.1
92.5
N.A.
91.7
90.8
N.A.
N.A.
66.8
50.9
49.6
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
55
96
95.1
N.A.
94.8
94.1
N.A.
N.A.
76.7
65.9
65.1
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
6.6
100
73.3
N.A.
73.3
73.3
N.A.
N.A.
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
80
N.A.
93.3
86.6
N.A.
N.A.
40
40
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
20
0
0
0
10
10
0
0
0
20
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
60
30
20
10
0
10
0
0
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
40
0
0
0
0
0
% F
% Gly:
70
0
0
0
0
0
10
10
0
0
10
70
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
10
0
0
80
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
20
0
0
40
0
10
0
0
20
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
0
10
0
10
10
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
20
0
0
0
0
0
0
% N
% Pro:
0
60
0
0
10
0
0
10
10
0
0
0
0
10
60
% P
% Gln:
10
0
10
0
0
0
20
0
10
10
0
0
0
0
0
% Q
% Arg:
10
0
0
20
0
10
30
40
20
0
60
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
20
30
10
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
40
0
0
0
0
0
0
10
80
0
% T
% Val:
0
20
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _